New, highly efficient formulation of diclofenac for the topical, transdermal administration in ultradeformable drug carriers, Transfersomes

Drug deliveryNSAIDTargeted applicationBiodistributionPharmacokineticsPhospholipid bilayerTransfenac, a lotion-like formulation of diclofenac, is described. It consists...

G Cevc，G Blume - 《Biochimica Et Biophysica Acta》

New, highly efficient formulation of diclofenac for the topical, transdermal administration in ultradeformable drug carriers, Transfersomes

Drug deliveryNSAIDTargeted applicationBiodistributionPharmacokineticsPhospholipid bilayerTransfenac, a lotion-like formulation of diclofenac, is described. It consists...

CG Blume - Biochimica et Biophysica Acta (BBA) - Biomembranes

Intra-articular drug delivery: The challenge to extend drug residence time within the joint

The rationale behind developing sustained release microsphere formulations of non-steroidal anti-inflammatory drugs (NSAIDs) administered via the intra-art...

SHR Edwards - 《Veterinary Journal》

Studies on the Development of Colon-targeted Delivery Systems for Celecoxib in the Prevention of Colorectal Cancer

The nonsteroidal anti-inflammatory drugs (NSAIDs) are found to be potential chemopreventive agents of colorectal cancer. Celecoxib, an NSAID with selective...

YSR Krishnaiah，V Satyanarayana，BD Kumar，... - 《Journal of Drug Targeting》

Studies on the Development of Colon-targeted Delivery Systems for Celecoxib in the Prevention of Colorectal Cancer.

The nonsteroidal anti-inflammatory drugs (NSAIDs) are found to be potential chemopreventive agents of colorectal cancer. Celecoxib, an NSAID with selective...

Krishnaiah，SR Y.，Satyanarayana，... - 《Journal of Drug Targeting》

Pharmaceutical compositions for the coordinated delivery of NSAIDs

The present invention is directed to drug dosage forms that release an agent that raises the pH of a patient's gastrointestinal tract, followed by a non-steroidal anti-inflammatory drug. The dosage form is designed so that the NSAID is n...

JR Plachetka - US

New Dosage Formulations for Targeted Delivery of Cyclo-Oxygenase-2 Inhibitors: Focus on Use in the Elderly.

NSAIDs are a widely used class of analgesic and anti-inflammatory drugs that act by inhibiting the cyclo-oxygenase (COX) enzyme. However, because of their ...

Bansal，S Shyam，Joshi，... - 《Drugs & Aging》

BIOPHARMACEUTICS & DRUG DISPOSITION Formulation and Evaluation of Chitosan Microspheres of Aceclofenac for Colon-Targeted Drug Delivery

The objective of this investigation was to develop novel colon specific drug delivery. Aceclofenac, a NSAID, was successfully encapsulated into chitosan mi...

SK Umadevi，R Thiruganesh，S Suresh，... - 《Biopharmaceutics & Drug Disposition》

Transdermal drug delivery system for non-steroidal anti inflammatory drugs: A review

For the treatment of pain and inflammation Non-steroidal anti-inflammatory drugs are themost frequently used medications, but because of number of side effects limit their uses.Transdermal drug delivery system (TDDS) provides sustain dru...

SV Kumar，P Tarun，TA Kumar - 《Indo American Journal of Pharmaceutical Research》

Controlled release drug delivery systems to improve post-operative pharmacotherapy

Over 230 million surgical procedures are conducted worldwide each year with numbers increasing. Pain, undesirable inflammation and infection are common com...

P Bhusal，J Harrison，M Sharma，... - 《Drug Delivery & Translational Research》