Selection and evolution of enzymes from a partially randomized non-catalytic scaffold.

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阅读量:

52

作者:

B SeeligJW Szostak

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摘要:

Enzymes are exceptional catalysts that facilitate a wide variety of reactions under mild conditions, achieving high rate-enhancements with excellent chemo-, regio- and stereoselectivities. There is considerable interest in developing new enzymes for the synthesis of chemicals and pharmaceuticals

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DOI:

10.1038/nature06032

被引量:

279

年份:

2007

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2008
被引量:39

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