AID is required for germinal center–derived lymphomagenesis
Most human B cell non-Hodgkin's lymphomas (B-NHLs) derive from germinal centers (GCs), the structure in which B cells undergo somatic hypermutation (SHM) a...
L Pasqualucci，G Bhagat，M Jankovic，... - 《Nature Genetics》
BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells
Theproto-oncogene encodes a transcriptional repressor that is required for germinal center formation and has been linked to lymphomagenesis. BCL6 functions...
RT Phan，M Saito，K Basso，... - 《Nature Immunology》
Nonrandom chromosome abnormalities in Iymphoma
G-banded chromosomes were studied from involved lymph nodes or other tumor masses in 94 patients with malignant lymphoma. Clonal chromosome abnormalities w...
CD Bloomfield，DC Arthur，G Frizzera，... - 《Cancer Research》
The human thymus contains a novel population of B lymphocytes.
A study of thymus glands from fetuses, newborn babies, children, and adults has shown a prominent intramedullary B-cell population. These cells have a distinctive phenotype, show evidence of activation, and specifically cluster around Ha...
PG Isaacson，AJ Norton，BJ Addis - 《Lancet》
There are differences in cytogenetic abnormalities among histologic subtypes of the non-Hodgkin's lymphomas
Although many recurring chromosome abnormalities have been found in malignant lymphoma (ML) in recent years, their relationship to histology remains largel...
EG Levine，DC Arthur，G Frizzera，... - 《Blood》
in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays
Leukemia is one of the leading journals in hematology and oncology. It is published monthly and covers all aspects of the research and treatment of leukemi...
C Mestre，F Rubio-Moscardo，A Rosenwald，... - 《Leukemia》
Histologic conversion in the non-Hodgkin's lymphomas.
Between July 1, 1971 and December 31, 1978, 150 patients with favorable subtypes of non-Hodgkin's lymphoma [nodular poorly differentiated lymphocytic (NLPD), nodular mixed, or diffuse well differentiated lymphocytic] were entered into pr...
B Acker，RT Hoppe，TV Colby，... - 《Journal of Clinical Oncology Official Journal of the American Society of Clinical Oncology》
CHAPTER 24 - Lymph Nodes: Cytomorphology and Flow Cytometry
Between July 1, 1971 and December 31, 1978, 150 patients with favorable subtypes of non-Hodgkin's lymphoma [nodular poorly differentiated lymphocytic (NLPD), nodular mixed, or diffuse well differentiated lymphocytic] were entered into pr...
- Comprehensive Cytopathology
CHAPTER 43 – Bone Marrow
Between July 1, 1971 and December 31, 1978, 150 patients with favorable subtypes of non-Hodgkin's lymphoma [nodular poorly differentiated lymphocytic (NLPD), nodular mixed, or diffuse well differentiated lymphocytic] were entered into pr...
D Arber - Elsevier Health Sciences
CHAPTER 41 – Lymph Nodes
Between July 1, 1971 and December 31, 1978, 150 patients with favorable subtypes of non-Hodgkin's lymphoma [nodular poorly differentiated lymphocytic (NLPD), nodular mixed, or diffuse well differentiated lymphocytic] were entered into pr...
K Chang，D Arber，L Weiss - Elsevier Health Sciences
