Activation of the SH2-containing receptorin vivo should result in stimulationof SH-PTP2 Phosphotyrosine Phosphatase activity. SH-PTP2by Its Binding Site, Phosphotyrosine 1009, on the Human Platelet-derivedGrowth Factor Receptor p*
摘要：
FIG1. . SH-PTP2 binds to the activated PDGFR at tyrosine1009. A, peptide competition of wild type PDGFR binding to GST-N-SH2. Lysates from PDGF-stimulated canine epithelialcells expressingthe wild type PDGFR (ATWT cells) were purified on glutathione-aga-
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