Characterization of the Pharmacokinetic and Pharmacodynamic Interaction between Gamma-Hydroxybutyrate and Ethanol in the Rat

It has been reported that ethanol enhances the hypnotic effect of gamma-hydroxybutyrate (GHB). In order to clarify the nature of this interaction we studie...

V Sassenbroeck，K D. - 《Toxicological Sciences》

Effect of low dose gamma-butyrolactone therapy on forebrain neuronal ischemia in the unrestrained, awake rat

Low dose () therapy alters the natural history of experimental forebrain in the awake . After 30 minutes of four-vessel , repeated cerebral blood flow dete...

MH Lavyne，RJ Hariri，T Tankosic，... - 《Neurosurgery》

The effects of gamma-hydroxybutyrate and gamma-butyrolactone upon the energy metabolism of the normoxic and hypoxic rat brain

MacMillan V.

V Macmillan - 《Brain Research》

Selective hydrogenation of maleic anhydride to γ-butyrolactone and tetrahydrofuran by Cu–Zn–Zr catalyst in the presence of ethanol

A series of Cu–Zn–Zr catalysts were prepared by a coprecipitation method and characterized by X-ray diffraction, X-ray photoelectron spectroscopy, temper...

D Zhang，H Yin，G Chen，... - 《Journal of Industrial & Engineering Chemistry》

gamma-Butyrolactone effects on behavior induced by dopamine agonists

gamma-Butyrolactone (GBL) potently inhibits stereotyped behavior induced by indirect (amphetamine and methylphenidate) and direct (apomorphine) dopamine agonists. Amphetamine induces a dose-response partial reversal of the GBL effect. Th...

EH Ellinwood，AE Gonzalez，GG Dougherty - 《Biological Psychiatry》

Polylactones, 50. The Reactivity of Cyclic and Noncyclic Dibutyltin Bisalkoxides as Initiators in the Polymerization of Lactones

Dibutyltin bisethoxide and bis(2,2,2-trifluoroethoxide), the cyclic alkoxides derived from cis -1,4-butenediol, 1,4-butanediol, 1,8-octanediol and triethyl...

HR Kricheldorf，A Stricker，D Langanke - 《Macromolecular Chemistry & Physics》

[A new drug of abuse: Gammabutyrolactone (GBL)]

The discovery of new psychoactive drugs for recreational purposes has been facilitated in recent years by access to the internet. Used in industry as a sol...

M Spadari，M Glaizal，L Tichadou，... - 《Presse Médicale》

Temporal and Potential Predictive Relationships between Sleep Spindle Density and Spike-and-Wave Discharges

To confirm such temporal relationship observed in these genetic model mice, we used a gamma-butyrolactone (GBL) pharmacological model of SWDs. Prior to ...

MS Abdelaal，T Kato，A Natsubori，... - 《Eneuro》

PROCESS FOR PRODUCING 1,4-BUTANEDIOL, GAMMA-BUTYROLACTONE AND TETRAHYDROFURAN IN THE GAS PHASE WHILE AVOIDING POLYMERIC DEPOSITS

The invention relates to an improved process for producing 1,4-butanediol, tetrahydrofuran and gamma-butyrolactone, wherein in the presence of hydrogen in ...

R Pinkos，D Rodewald，SS Linke，...