Toward a Comprehensive Map of the Effectors of Rab GTPases

作者:

A GillinghamR SinkaI TorresK LilleyS Munro

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摘要:

Rab GTPases organize cellular compartments by recruiting specific effectors to organelle membranes. This paper describes affinity chromatography using all Drosophila Rabs with a mammalian ortholog. The Rab interactors found include known effectors, tethering complexes, coiled-coil proteins, motor proteins, proteins of unknown function, and several proteins linked to human disease.

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DOI:

10.1016/j.devcel.2014.10.007

被引量:

101

年份:

2014

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来源期刊

Developmental Cell
2014/11/10

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2016
被引量:33

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