Microarray synthesis and assembly of gene-length polynucleotides
申请(专利)号:
PCT/US2003/028946
申请日期:
20030912
公开/公告号:
WO2004024886A2
申请(专利权)人:
国省代号:
WO
被引量:
摘要:
There is disclosed a process for in vitro synthesis and assembly of long, gene-length polynucleotides based upon assembly of multiple shorter oligonucleotides synthesized in situ on a microarray platform. Specifically, there is disclosed a process for in situ synthesis of oligonucleotide fragments on a solid phase microarray platform and subsequent, on device assembly of larger polynucleotides composed of a plurality of shorter oligonucleotide fragments.
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