Administering botulinium toxin component coupled to substance p

阅读量:

19

公开/公告号:

US7622127 B2

公开/公告日期:

Dec 31, 2002

发明人:

S Donovan

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被引量:

121

摘要:

Agents for treating pain, methods for producing the agents and methods for treating pain by administration to a patient of a therapeutically effective amount of the agent. The agent can include a clostridial neurotoxin, or a component or fragment or derivative thereof, attached to a targeting moiety, wherein the targeting moiety is selected from a group consisting of transmission compounds which can be released from neurons upon the transmission of pain signals by the neurons, and compounds substantially similar to the transmission compounds.

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2013
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