Mechanisms of cell fusion
摘要:
WE report new findings on the chemically-induced fusion of hen erythrocytes and discuss possible ways in which the lipid and protein/glycoprotein components of membranes may behave during the process of membrane fusion. Our observations are consistent with Poste and Allison'sidea that the aggregation of intrinsic membrane proteins is important in membrane fusion but we suggest that fusion may occur in regions of perturbed lipid bilayer which are thus denuded of intramembranous particles.
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关键词:
Experimental/ blood cellular biophysics macromolecules membranes molecular biophysics organic compounds proteins/ chemically induced fusion hen erythrocytes lipid protein glycoprotein membrane fusion dimethyl sulphoxide glycerol mechanisms of cell fusion/ A8715 Molecular biophysics A8720 Membrane biophysics A8725 Cellular biophysics
DOI:
10.1038/253194a0
被引量:
年份:
1975
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