Anthropomorphic 1H MRS head phantom

来自 NCBI

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作者：

JR Rice，RH Milbrandt，EL Madsen，GR Frank，EJ Boote，JC Blechinger

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摘要：

An anthropomorphic 1H MRS head phantom has been developed which mimics the in vivo structure, metabolite concentrations, and relaxation times (for both water and metabolites) of human brain tissue. Different brain regions and two tumor types, fluid-containing ventricles, and air-filled sinus, and subcutaneous fat are all simulated. The main tissue-mimicking materials are gelatin/agar mixtures with metabolites and several other ingredients added. Their composition and method of production are thoroughly described. T1's and T2's of water in the phantom are very close to in vivo values, and metabolite T1's and T2's are considerably more realistic than those in aqueous solutions. Spectra and relaxation times for the pig brain were also acquired and compare well with those of the phantom. The realistic properties of this phantom should be useful for testing spectral quantitation and localization.

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关键词：

magnetic resonance spectroscopy phantoms tissue‐mimicking relaxation times Spectroscopy Static and low‐frequency electric and magnetic fields effects Submillimeter wave, microwave and radiowave spectrometers magnetic resonance spectrometers, auxiliary equipment, and techniques biomedical NMR NMR spectroscopy brain biomedical equipment nuclear spin‐lattice relaxation spin‐spin relaxation 87.58.12 87.55.08 Brain Relaxation times Testing procedures Tissues Cancer Physicists Spectral properties