Enantioselective conjugate addition of rationally designed chiral cuprate reagents to 2-cycloalkenones

阅读量:

41

作者:

EJ CoreyR NaefFJ Hannon

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摘要:

Results of an initial investigation are described, demonstrating for the first time the possibility of achieving enantioselectivities (75-95%) with a simple chiral controller ligand (III), obtainable in one step in either enantiomeric form from (+)- or (-)-ephedrine (I).

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DOI:

10.1002/chin.198712091

被引量:

416

年份:

1987

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