Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating B cell neoplasm
申请(专利)号:
CA20062609062
申请日期:
2006-02-13
公开/公告号:
CA2609062A1
公开/公告日期:
2006-11-23
申请(专利权)人:
CHANGCHUN HUAPU BIOTECHNOLOGY CO., LTD.
被引量:
摘要:
The invention provides nine oligonuleotides with sequences of SEQ ID NO:1-9 or their functional homologues or a composition comprising the same and a method for treating B cell neoplasm by using the oligonuleotides or their functional homologues or the composition comprising the oligonuleotides. The oligonuleotides induce the apoptosis of B cell neoplastic cells, up-regulate CD40 on B cell neoplastic cells and stimulate the production of IL-10 from B cell neoplastic cells.
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