Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating B cell neoplasm

阅读量:

36

申请(专利)号:

CA20062609062

申请日期:

2006-02-13

公开/公告号:

CA2609062A1

公开/公告日期:

2006-11-23

申请(专利权)人:

CHANGCHUN HUAPU BIOTECHNOLOGY CO., LTD.

发明人:

Li-Ying WangMS BaoYL Yu

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被引量:

2

摘要:

The invention provides nine oligonuleotides with sequences of SEQ ID NO:1-9 or their functional homologues or a composition comprising the same and a method for treating B cell neoplasm by using the oligonuleotides or their functional homologues or the composition comprising the oligonuleotides. The oligonuleotides induce the apoptosis of B cell neoplastic cells, up-regulate CD40 on B cell neoplastic cells and stimulate the production of IL-10 from B cell neoplastic cells.

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