摘要：

Focuses on the identification of resistin, a signalling molecule involved in insulin resistance secreted by adipocytes. Regulation by thiazolidinediones; Downregulation and neutralization of resistin; Action of impairing glucose tolerance in vivo and antagonizing insulin action in vitro; Experiments on diet-induced and genetically obese mice; Potential role of resistin in a link between obesity and diabetes.

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