T lymphoblastic lymphoma with LEU-7 positive phenotype and unusual clinical course: a multiparameter study.
摘要:
Immunologic phenotype studies were performed on cells and on frozen sections of involved tissue from a 20 year old female with typical T-cell lymphoblastic (convoluted) lymphoma. The cells demonstrated a thymic phenotype but in addition marked with Leu-7 (HNK-1) — an antibody reported to identify human natural killer/killer (NK/K) cells. Normal or neoplastic cells with this phenotype have not been previously reported. These findings support the existence of a thymic precursor for a T-cell subset of Leu-7 + cells. The unusual clinical response to therapy is another feature of this unique case.
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DOI:
10.1016/0145-2126(85)90030-X
被引量:
年份:
1985
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