摘要：

Stereoselective synthesis of an enantiomeric pair of the ABC-ring system of quinocarcin(1), a notable antitumor antibiotic, could be achieved in > 95%ee by utilizing each enantiomer of 4-O-benzyl-2,3-O-isopropylidene-threose as a chiral auxiliary and featuring novel diastereoselective reduction of the 1,3-disubstituted isoquinoline as a key step.

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