Bioactive sesquiterpenes from a Taiwanese marine sponge Parahigginsia sp.
摘要:
Five new sesquiterpenes, parahigginols A-D (1-4) and parahigginic acid (5), have been isolated from a Taiwanese marine sponge Parahigginsia sp. The structural assignments of the new compounds were based on their spectral data, including 1D and 2D NMR. Biological studies revealed that compounds 2-5 exhibited cytotoxicity against murine P-388 and human KB16, A549, and HT-29 tumor cells.
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DOI:
10.1021/np980491p
被引量:
年份:
1999
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