摘要：

The use of one equivalent of benzylamine increased the enantioselectivity in the heterogeneous catalytic hydrogenation of α,β α , β mathContainer Loading Mathjax -unsaturated carboxylic acids over cinchonidine-modified 5% Pd/Al 2 O 3 catalyst. The beneficial effect of the amine additive was dependent on substrate structure. The highest effect, a more than sixfold increase in the enantiomeric excess, was obtained in the hydrogenation of itaconic acid. This is the first report on the enantioselective hydrogenation of a prochiral α,β α , β mathContainer Loading Mathjax -unsaturated dicarboxylic acid over a supported heterogeneous metal catalyst.

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