Applications of capillary zone electrophoresis in separation of enantiomers in chiral drugs
摘要:
The separation of enatiomers in chiral drugs is an important subject of research in pharmaceutical field.Because enantiomers have similar physio-chemical properties,their separation is very difficult.Capillary electrophoresis(CE)has been widely applied to the enantioseparation of chiral drugs owing to its high efficiency,rapid analysis,and low buffer and sample consumption,etc.The capillary zone electrophoresis(CZE)is the most commonly used separation mode.This paper briefly reviews the applicatins of CZE for the enatioseparation of chiral drugs.The development of CZE in this field is discussed.
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年份:
2009
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