Proof of Principle in the Selective Treatment of Cancer by Antibody‐Directed Enzyme Prodrug Therapy: The Development of a Highly Potent Prodrug
摘要：
Perfectly adept for tumor treatment: With the seco-CBI-Q galactoside 1 a novel highly potent prodrug for the selective treatment of cancer using the ADEPT approach was developed, which shows very promising results in preclinical trials on a human bronchial carcinoma in SCID mice (see picture; lung tissue after (A) and before treatment (B)).
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DOI：
10.1002/1521-3773(20020301)41:53.0.CO;2-7
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年份：
2002
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来源期刊
Angew Chem Int Ed Engl
2002-03-01
引用走势
2010
被引量：53
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