Production of (+)‐(S)‐Ethyl 3‐Hydroxybutyrate and (‐)‐(R)‐Ethyl 3‐Hydroxybutyrate by Microbial Reduction of Ethyl Acetoacetate
摘要：
The production of ( S )-ethyl 3-hydroxybutyrate (2) from ethyl acetoacetate (1) in higher yields and with higher optical purity than with the usual procedures was achieved by continuous addition of the substrate 1 and sucrose to an aerated suspension of bakers' yeast. The microbial reduction of 1 by the fungus Geotrichum candidum LINK yields - for the first time - the antipode 3 .
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DOI：
10.1002/hlca.19830660209
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年份：
1983
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来源期刊
Helvetica Chimica Acta
1983/03/16
引用走势
2010
被引量：56
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