Reactive Oxygen-Mediated Protein Oxidation in Aging and Disease
摘要:
The fast reaction of peroxynitrite with CO2 and the high concentration of dissolved CO2 in vivo (ca. 1 mM) suggest that CO2 modulates most of the reactions of peroxynitrite in biological systems. The addition of peroxynitrite to CO2 produces of the adduct ONOO-CO2- (1). The production of 1 greatly accelerates the decomposition of peroxynitrite to give nitrate. We now show that the formation of...
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DOI:
10.1007/0-306-46806-9_27
被引量:
年份:
2002
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