The versatility of mitochondrial calcium signals: From stimulation of cell metabolism to induction of cell death
摘要:
Both the contribution of mitochondria to intracellular calcium (Ca2+) signalling and the role of mitochondrial Ca2+ uptake in shaping the cytoplasmic response and controlling mitochondrial function are areas of intense investigation. These studies rely on the appropriate use of emerging techniques coupled with judicious data interpretation to a large extent. The development of targeted probes based on the molecular engineering of luminescent proteins has allowed the specific measurement of Ca2+ concentration ([Ca2+]) and adenosine trisphosphate concentration ([ATP]) in intracellular organelles or cytoplasmic subdomains. This approach has given novel information on different aspects of mitochondrial homeostasis.
展开
关键词:
Cells Mitochondria Animals Calcium Luciferases Adenosine Triphosphate Signal Transduction Cell Death Biological Transport Homeostasis
DOI:
10.1016/j.bbabio.2008.05.449
被引量:
年份:
2008









































通过文献互助平台发起求助,成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
来源期刊
引用走势
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用!