PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease
摘要:
These results identify FGF14 as a potential PPARγ-sensitive target controlling Aβ-induced dysfunctions of neuronal activity in the DG underlying memory loss in early AD.
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关键词:
Alzheimer's disease PPARgamma Fibroblast growth factor 14 Mass spectrometry Confocal microscopy
DOI:
10.1016/j.expneurol.2017.05.005
被引量:
年份:
2017
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