摘要：

Relationships between K binding and oxidative phosphorylation were observed in intact mitochondria and in mitochondrial fragments. In the case of the intact mitochondria, evidence that the 2 processes are linked derives primarily from consideration of a common dependence of these functions upon the relative intactness of the mitochondrial structure. Experiments were also carried out which employ a preparation of smaller particle size derived from mitochondria that have been disrupted with digitonin. These mitochondrial fragments, which catalyze phophorylation, also retain the capacity to bind K. Respiration via the cytochrome system preserved bound K and increased the rate of exchange with radiopotassium of the medium. These effects did not appear to be dependent upon the presence of adenosine triphosphate or its active synthesis, but were abolished by 2,4-dinitrophenol. The probability of an association between the K binding site and the enzymes responible for coupling oxidation to phosphorylation is discussed.: The vesicular stage was absent in the development of cutaneous lesions in sheep. Instead of the characteristic pustule formation, a zone of suppuration was observed in between the necrosed crust and the underlying granulation tissue. Significant p...: Motivation: Errors in nucleotice sequence and SNP genotyping data are problematic when inferring haplotypes. Previously published methods for error detection in haplotype data make use of pedigree information; however, for many samples, individua...: Residual toxicity and leaf protection capability of five pyrethroids, professional and home garden azadirachtin formulations, and six other bioinsecticides for the home landscape were evaluated against the Japanese beetle, Popillia japonica Newman...: We describe a rapid transient assay system for analysing the efficacy of diphtheria toxin A chain (DT-A) derivatives as agents of genetic cell ablation in plant tissues. Because of the extreme cytotoxic effects of DT-A in eukaryotic cells we are i...: The development of anorexia nervosa in a high-functioning, early adolescent, autistic female is described. This case raises the issue of co-occurrence of childhood-onset disorders sharing the phenomena of obsessions and compulsions. The role of dy...: Pruritus is the most common side effect of intrathecal morphine for postoperative pain relief. Activation of central 5-hydroxytryptamine subtype 3 (5-HT3) receptors is one of its possible mechanisms. The role of 5-HT3 antagonists in the prevention...: An animal model was used to examine local and systemic cellular reactivity against virus infection of bowel mucosa. Firstly, existing techniques for extracting lymphoid cells from the dispersed populations of the bowel mucosa were adapted for use...: Components of the benzene extract of knots of dead trees from Araucaria, Brazil, were identified.

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