Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor compound

阅读量:

23

申请(专利)号:

07/995252

申请日期:

12/22/1992

公开/公告号:

US5356896

公开/公告日期:

10/18/1994

发明人:

MB KabadiRV Vivilecchia

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被引量:

407

摘要:

A pharmaceutical dosage form comprising an HMG-CoA reductase inhibitor compound, e.g., fluvastatin sodium, is disclosed which is stabilized against pH-related degradation by an alkaline stabilizing medium capable of imparting a pH of at least 8 to an aqueous solution or dispersion of the composition.

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2008
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