Iron status is associated with carotid atherosclerotic plaques in middle-aged adults.

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41

摘要:

Although the iron-heart disease hypothesis is prevalent, the epidemiological findings are incongruent. The relationship of serum ferritin with early cardiovascular disease (CVD), particularly atherosclerosis, has not been evaluated extensively, particularly with accounting for inflammation, We examined this association in a case-control study of 124 age- and sex-matched pairs embedded in the population-based random sample (MONICA survey) in Southwest France, taking into account inflammation status. Cases had ≥2 carotid atherosclerotic plaques and controls had none. Inflammation was assessed using several markers, including serum α-1 acid glycoprotein (AGP) and high sensitivity C-reactive protein. There was an interaction of inflammation with group (case/control) for serum ferritin. In

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DOI:

10.3945/jn.109.110353

被引量:

71

年份:

2010

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2013
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