The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene.
摘要:
E-cadherin-mediated cell-cell adhesion is lost during the development of most epithelial cancers. Recent evidence indicates that the loss of E-cadherin function, besides causing loss of cell-cell adhesion, might also convey signals that actively induce tumour-cell invasion and metastasis.
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关键词:
Animals Humans Neoplasms Neoplasm Invasiveness Cadherins Cell Adhesion Signal Transduction Homeostasis Genes, Tumor Suppressor
DOI:
10.1016/S0968-0004(98)01343-7
被引量:
年份:
1999






























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