BLOCKERS OF GSK3 FOR THE PREVENTION AND TREATMENT OF PEMPHIGUS VULGARIS
申请(专利)号:
WO2007EP06464
申请日期:
2007-07-20
公开/公告号:
WO2008012031A3
公开/公告日期:
2008-04-17
申请(专利权)人:
UNIVERSITAET BERN;MUELLER, ELIANE
摘要:
The invention relates to a method of preventing and treating pemphigus vulgaris comprising administering a GSK3 blocker, and the use of such blockers in said prevention and treatment and in the manufacture of medicaments for preventing and treating pemphigus vulgaris. In particular the invention relates to a method of preventing and treating pemphigus vulgaris comprising administering a GSK3 blocker, and the use of such blockers in said prevention and treatment and in the manufacture of medicaments for preventing and treating pemphigus vulgaris. Preferred is the use of GSK3 blockers which are selective for GSK3, i.e. which selectively reduce enzyme activity of GSK3 but not to a reasonable extent of GSK3a.
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