Enantioselective alkynylation of a prochiral ketone catalyzed by C2-symmetric diamino diols.
摘要:
C2-Symmetric diamino diols were used as chiral ligands to induce the asymmetric addition of lithium acetylides to carbonyl groups. The enantiomeric excesses (up to 99% ee) depended on the structure of the acetylene.[Copyright &y& Elsevier]
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年份:
2002
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