The relationship between misonidazole cytotoxicity and base composition of DNA
摘要：
The damage induced by electrolytically reduced misonidazole on DNAs of varying base composition has been measured. Damage assessment using a variety of techniques including viscometry, helix renaturation, hydroxyapatite chromatography and agarose gel electrophoresis indicates that damage is related to A + T content, suggesting that misonidazole cytotoxicity involves a specific target in DNA.
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DOI：
10.1016/0006-2952(80)90178-1
被引量：
年份：
1980
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