Cyclosporin A protects against ischemia-reperfusion injury in the brain.
摘要：
We investigated the protective effect of Cyclosporin A (CsA) against ischemia-reperfusion injury in the brain using a transient focal ischemia model in rats. In CsA-treated rats, ischemic brain edema formation 1 day after reperfusion in the cerebral cortex perfused by the middle cerebral artery (MCA) and infarct size were decreased compared with those in olive oil treated control rats. These results suggest that CsA is beneficial in reducing ischemia-reperfusion injury, possibly by the suppression of immunological reactions.
展开
关键词：
Animals Rats Rats, Wistar Cerebral Arteries Brain Edema Brain Injuries Reperfusion Injury Cyclosporine Alanine Transaminase Aspartate Aminotransferases
DOI：
10.1016/0006-8993(92)91465-Q
被引量：
年份：
1992
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
