On the repetitive discharge in myotonic muscle fibres
摘要：
1. Muscle fibres from myotonic respond to injected constant currents with a train of action potentials. If the number of action potentials in an evoked train exceeds 10-15, stopping the current does not stop the repetitive firing of action potentials.2. Normal muscle fibres () in a -free Ringer respond in the same way to constant current.3. In the absence of self-maintained activity both myotonic fibres and normal fibres in -free Ringer show an after-depolarization which is proportional to the number of driven impulses. The half-time for the decay of this after-potential is about 0.5 sec.4. Tubular accumulation resulting from the initially driven activity and the known low conductance of myotonic muscle fibres appear to account for the initiation of the myotonic discharge.
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关键词：
Animals Goats Muscles Myotonia Congenita Glycerol Chlorides Potassium Biological Transport, Active Action Potentials Time Factors
DOI：
10.1113/jphysiol.1974.sp010620
被引量：
年份：
1974
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