Protein S-nitrosylation: purview and parameters.

来自 EBSCO

阅读量:

333

作者:

DT HessA MatsumotoSO KimHE MarshallJS Stamler

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摘要:

S-nitrosylation, the covalent attachment of a nitrogen monoxide group to the thiol side chain of cysteine, has emerged as an important mechanism for dynamic, post-translational regulation of most or all main classes of protein. S-nitrosylation thereby conveys a large part of the ubiquitous influence of nitric oxide (NO) on cellular signal transduction, and provides a mechanism for redox-based physiological regulation.

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DOI:

10.1038/nrm1569

被引量:

3210

年份:

2005

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