Conformationally Flexible Biphenyl‐phosphane Ligands for Ru‐Catalyzed Enantioselective Hydrogenation
摘要：
Stereomutation of a BIPHEP/RuCl 2 /diamine complex (shown schematically) is possible because of the conformational flexibilty of BIPHEP ligands. The result is an asymmetric activation in the Ru-catalyzed hydrogenation of carbonyl compounds to optically active alcohols. Whereas a racemic BINAP/RuCl 2 complex with a chiral diamine activator gives a 1:1 mixture of two diastereomers, unequal amounts of the diastereomers can be produced from a BIPHEP/RuCl 2 complex and a chiral diamine. Ar=3,5-dimethylphenyl, BINAP=2,2′-bis(diphenylphosphanyl)-1,1′-binaphthyl, BIPHEP=2,2′-bis(diarylphosphanyl)biphenyl.
展开
DOI：
10.1002/(SICI)1521-3773(19990215)38:43.0.CO;2-O
被引量：
年份：
1999
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
