Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility.
摘要：
Examines the role of adducin phosphorylation by Rho-kinase in membrane ruffling regulation and cell motility. Identification of Thr445 and Thr480 as the phosphorylation sites of phosphorylation; Accumulation of phosphorylated alpha-adducin at the ruffling membrane areas and leading edge of scattering cells; Regulation of alpha-adducin function through phosphorylation.
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1999
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2009
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