Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.

Little is known about the biochemical environment in phagosomes harboring an infectious agent. To assess the state of this organelle we captured the transc...

D Schnappinger，S Ehrt，MI Voskuil，... - 《Journal of Experimental Medicine》

Insect hemocytes and their role in immunity

This chapter surveys the classification of hemocytes and their origins and functions. Insect hemocytes are identified by a combination of morphological, an...

MR Strand

Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death.

Escherichia coli strains recovered from Crohn's disease (CD) lesions are able to adhere to and invade cultured intestinal epithelial cells. We analyzed the...

AL Glasser，J Boudeau，N Barnich，... - 《Infection & Immunity》

Nanocarriers' entry into the cell: relevance to drug delivery

Nanocarriers offer unique possibilities to overcome cellular barriers in order to improve the delivery of various drugs and drug candidates, including the ...

H Hillaireau，P Couvreur - 《Cellular & Molecular Life Sciences》

Dendritic Cells Discriminate between Yeasts and Hyphae of the Fungus Candida albicans

The fungusCandida albicansbehaves as a commensal as well as a true pathogen of areas highly enriched in dendritic cells, such as skin and mucosal surfaces....

 - 《Journal of Experimental Medicine》

Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages.

Phagocytosis is a key aspect of our innate ability to fight infectious diseases. In this study, we have found that fusion of the endoplasmic reticulum (ER)...

E Gagnon，S Duclos，C Rondeau，... - 《Cell》

Innate Immunity to Mycobacterium tuberculosis

The different manifestations of infection with Mycobacterium tuberculosis reflect the balance between the bacillus and host defense mechanisms. Traditional...

RV Crevel，THM Ottenhoff，JWMVD Meer - 《Advances in Experimental Medicine & Biology》

Innate Immunity to Mycobacterium Tuberculosis

The different manifestations of infection with Mycobacterium tuberculosis reflect the balance between the bacillus and host defense mechanisms. Traditional...

RV Crevel，THM Ottenhoff，JWMVD Meer - 《Advances in Experimental Medicine & Biology》

The mannose receptor family

The mannose receptor family comprises four glycoproteins each of which is a type I transmembrane receptor with an N-terminal cysteine-rich domain, a single...

L East，CM Isacke - 《Biochim Biophys Acta》

Phagosome maturation: aging gracefully.

Foreign particles and apoptotic bodies are eliminated from the body by phagocytic leucocytes. The initial stage of the elimination process is the internali...

O Vieira，R Botelho，S Grinstein - 《Biochemical Journal》