Segmented absorbable copolymer

来自 FreePatentsOnline

喜欢 0

阅读量：

申请(专利)号：

07/548801

申请日期：

07/06/1990

公开/公告号：

US5252701

公开/公告日期：

10/12/1993

申请(专利权)人：

American Cyanamid Company (Stamford, CT)

发明人：

PK Jarrett，L Rosati，DJ Casey

展开

被引量：

163

摘要：

A copolymer comprising a bioabsorbable, segmented molecular architecture has been invented. The copolymer has at least two different ester linkages. The segmented molecular architecture comprises a plurality of fast transesterifying linkages. The fast transesterifying linkages have a segment length distribution of greater than 1.3. The segmented molecular architecture also comprises a plurality of slow transesterifying linkages. The following proviso is a material limitation to this invention: for the fast transesterifying linkages consisting essentially of glycolate linkages and the slow transesterifying linkages selected from the group consisting of trimethylene carbonate and caproate linkages, the segment length distribution of the fast transesterifying linkages is up to 2.0 and the number average segment length of the slow transesterifying linkages is greater than 2.5 linkages per segment. The copolymer is useful as an article of manufacture, for example a molding resin, surgical element and controlled release device.

展开