The Morphological Classification of Acute Lymphoblastic Leukaemia: Concordance among Observers and Clinical Correlations
摘要：
Summary. The degree of concordance in the morphological classification of ALL was assessed by the FAB group after two successive reviews of 200 and 100 slides respectively. As a result, a simple scoring system for types L1 and L2 is proposed based on the following four features: (1) nuclear cytoplasmic ratio, (2) presence, prominence and frequency of nucleoli, (3) regularity of nuclear membrane outline, and (4) cell size. By this method, the overall concordance by seven observers (agreement of 7:0 or 6:1 only) increased from 63% to 84%.
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DOI：
10.1111/j.1365-2141.1981.tb02684.x
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年份：
1981
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