Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
Disclosed are drug delivery systems based on a polymeric component which is soluble or insoluble (cross-linked) hyaluronan or hyaluronan copolymerized with another hydrophilic polymer or hylan and one or more substances having biological...
EA Balazs，A Leshchiner，NE Larsen - US
Injectable polymeric bodies
An injectable composition consisting of a plurality of discrete physiologically-compatible, non-biodegradable, silicone rubber bodies, said bodies having (i) a maximum outside dimension of from about 0.005 to 0.08 inch (125 to 2000&mgr;)...
EP Berg - EP
Crosslinked polysaccharides, medical use
Disclosed are biocompatible viscoelastic gel slurries formed from a polymeric gel, preferably a hyaluronan or a derivative thereof such as hylan swollen in...
E Leshchiner，EA Balazs，NE Larsen，... - US
Water insoluble derivatives of hyaluronic acid
A method for making a water insouble bicompatible gel includes activating HA with an activating agent to form activated HA, and reacting the activated HA with a nucleophile, under conditions producing the water insoluble bicompatible gel...
R Hamilton，Ellen M. Fox，Raksha A. Acharya，... - EP
Biocompatible viscoelastic gel slurries, their preparation and use
Disclosed are biocompatible viscoelastic gel slurries formed from a polymeric gel, preferably a hyaluronan or a derivative thereof such as hylan swollen in an aqueous medium and a fluid phase which is an aqueous solution of a polymer whi...
E Leshchiner，EA Balazs，NE Larsen，... - EP
A composition and a method for tissue augmentation
The present invention provides a biocompatible composition for tissue augmentation, comprising a pseudoplastic polymer carrier in an amount of 0.05-50 % (w/w) of the total composition; and one or more tissue augmenting substance(s). Furt...
AAGERUP BENGT - WO
Biocompatible viscoelastic gel slurries, their preparation and use
Disclosed are biocompatible viscoelastic gel slurries formed from a polymeric gel, preferably a hyaluronan or a derivative thereof such as hylan swollen in an aqueous medium and a fluid phase which is an aqueous solution of a polymer whi...
E Leshchiner，EA Balazs，NE Larsen，... - EP
Method for structure for situating in a living body agents for treating the body
By way of a suitable syringe, for example, there is injected into the tissue of a living being an absorbable viscous substance in which a plurality of solid bodies are suspended to an extent sufficient to be distributed throughout the vi...
L Bucalo - US
Gel of crosslinked hyaluronic acid for use as a vitreous humor substitute
The invention is concerned with a vitreous humor substitute intended for ophthalmological uses and consisting of a gel of crosslinked hyaluronic acid and a method at retinal surgery and after vitrectomy when the vitreous humor completely...
T Malson，BL Lindqvist - WO
Polymeric compositions and methods of using them
Dispersions in water-immiscible liquid of water-soluble or water- swellable polymer particles are stabilized by use of an aqueous emulsion of water insoluble viscosifying polymer particles that are swellable or soluble in the water-immis...
B Dymond，J Langley，M Hawe - US
