Low molecular weight protein tyrosine phosphatases as therapeutic targets and diagnostic (LMW-PTP)
申请(专利)号:
JP2004506837
申请日期:
20030522
公开/公告号:
JP2006501153A
公开/公告日期:
20060112
申请(专利权)人:
パーデュー・リサーチ・ファウンデーション
摘要:
Diagnosis of cancer, I identified as a therapeutic target and newly diagnosed in the treatment and prognosis, low molecular weight protein tyrosine phosphatase (LMW-PTP). And LMW-PTP, optionally, the invention provides methods of diagnosis and treatment useful in the context of cancer expressing EphA2 receptor. It also provides a screening method that utilizes the change of the amount and the activity of the LMW-PTP and / or in order to identify the cancer therapeutic agents of candidates to be targeted to enable the oncogenic protein EphA2.
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