Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: A co-expression meta-analysis
摘要：
Amyloid plaques in Alzheimer's disease (AD) mice are surrounded by activated microglia. The functional role of microglia activation in AD is not well understood; both detrimental and beneficial effects on AD progression have been reported. Here we show that the population of activated microglia in the cortex of the APPswe/PS1dE9 mouse AD model is divided into a CD11c-positive and a...
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DOI：
10.1186/s40478-015-0203-5
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年份：
2015
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