Adhesive preparation containing fentanyl
公开/公告号：
CN1732937 A
公开/公告日期：
2006年2月15日
被引量：
摘要：
本发明提供一种包含芬太尼的可经皮吸收的粘合剂制剂,该制剂是从经济的原材料获得的,具有比常规制剂简化的构造,有足够的皮肤通透性,并且该制剂可以通过改变两种具有不同分子量的聚异丁烯,增粘剂和有机液体的比率来控制皮肤通透性. The present invention provides a composition comprising fentanyl, adhesive percutaneously absorbed preparation which is obtained from an economical material, having a simplified structure than conventional formulations, sufficient skin permeability, and the preparation can By changing the two kinds of polyisobutylene having different molecular weights, a tackifier and an organic liquid to control the ratio of the permeability of the skin. 具体而言,本发明提供一种可以经皮吸收的粘合剂制剂,该制剂包含载体和层压在载体一个表面上的粘合剂层,其中粘合剂层包含芬太尼,两种具有不同分子量的聚异丁烯,增粘剂以及和上述两种聚异丁烯及上述增粘剂相容的有机液体. Specifically, the present invention provides a percutaneously absorbable adhesive preparation which comprises a support and laminated on the pressure-sensitive adhesive on one surface of the carrier layer, wherein the adhesive layer comprises fentanyl, the two having different molecular weight polyisobutylene, a tackifier, and polyisobutylene and the two of the above organic liquid compatible tackifier.
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