The Bcl-2 family and cell death regulation
摘要：
Members of the Bcl-2 protein family fall into two categories on the basis of their ability to either promote or suppress apoptosis. Recent findings have linked these proteins to caspases, the cysteine proteases that effect the collapse of the cell via binding to CED-4. It seems that Bcl-2 proteins influence cell survival by regulating the activation of key caspases.
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关键词：
Animals Mice, Transgenic Humans Mice Cytochrome c Group Calcium-Binding Proteins Helminth Proteins Caenorhabditis elegans Proteins Proto-Oncogene Proteins c-bcl-2 Apoptosis
DOI：
10.1016/S0959-437X(98)80064-6
被引量：
年份：
1998
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