The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp inse...

A stoichiometric complex formed between human alpha-thrombin and D-Phe-Pro-Arg chloromethylketone was crystallized in an orthorhombic crystal form. Orienta...

Bode，Mayr，Baumann，... - 《Embo Journal》

Protein inhibitors of cysteine proteinases. II. Primary structure of stefin, a cytosolic protein inhibitor of cysteine proteinases from human polymorphonuc...

The primary structure of stefin, a new cysteine proteinase inhibitor from the cytosol of human polymorphonuclear granulocytes, was determined by amino-acid...

W Machleidt，U Borchart，H Fritz，... - Hoppe-Seyler´s Zeitschrift für physiologische Chemie

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. Crystal structure determination and stereochemistry of the conta...

The structure of the complex of bovine trypsin and bovine pancreatic trypsin inhibitor has been determined by crystal structure analysis at 2.8 脜 resoluti...

A Rühlmann，D Kukla，P Schwager，... - 《Journal of Molecular Biology》

Early incorporation of cell-derived cholesterol into pre-beta-migrating high-density lipoprotein.

Cultures of human skin fibroblasts were labeled to high cholesterol specific activity with [3H]cholesterol and incubated briefly (1-3 min) with normal huma...

GR Castro，CJ Fielding - 《Biochemistry》

Structure of the Complex Formed by Bovine Trypsin and Bovine Pancreatic Trypsin Inhibitor Refinement of the Crystal Structure Analysis

The serine proteinases and their natural inhibitors interact very strongly and specifically. There is evidence that enzymatic catalysis is involved in this...

R Huber，D Kukla，W Steigemann，... - Springer Berlin Heidelberg

The geometry of the reactive site and of the peptide groups in trypsin, trypsinogen and its complexes with inhibitors

First page of article

M Marquart，J Walter，J Deisenhofer，... - 《Acta Crystallographica》

The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.

The crystal structure of chicken egg white cystatin has been solved by X-ray diffraction methods using the multiple isomorphous replacement technique. Its ...

W Bode，R Engh，D Musil，... - 《Embo Journal》

Solution Conformation of Proteinase Inhibitor IIA from Bull Seminal Plasma by 1 H Nuclear Magnetic Resonance and Distance Geometry

A determination of the solution conformation of the proteinase inhibitor IIA from bull seminal plasma (BUSI IIA) is described. Two-dimensional nuclear Overhauser enhancement spectroscopy (NOESY) was used to obtain a list of 202 distance ...

MP Williamson，TF Havel，K Wüthrich - Solution Conformation of Proteinase Inhibitor IIA from Bull Seminal Plasma by 1 H Nuclear Magnetic Resonance and Distance Geometry

Refinement of the solution structure of the DNA hexamer 5'd(GCATGC)2: combined use of nuclear magnetic resonance and restrained molecular dynamics

The solution structure of the self-complementary DNA hexamer 5'd(GCATGC)2 comprising the specific target site for the restriction endonuclease Sph 1 is inv...

Michael，Nilges，G.，... - 《Febs Letters》

X-ray crystal structure of the complex of human leukocyte elastase (PMN elastase) and the third domain of the turkey ovomucoid inhibitor.

Orthorhombic crystals diffracting beyond 1.7 A resolution, have been grown from the stoichiometric complex formed between human leukocyte elastase (HLE) an...

W Bode，Wei, A.Z.，R Huber，... - 《Embo Journal》