Ultrasound in organic synthesis. 7. Preparation of organozinc reagents and their nickel-catalyzed reactions with .alpha.,.beta.-unsaturated carbonyl compounds
摘要:
Diorganozinc compounds can be prepared with great ease and efficiency in a one-pot process, by sonication of lithium, an organic halide, and a zinc halide in THF or toluene THF mixtures. The reagents thus obtained give rise to clean and selective conjugate additions to α,β-unsaturated aldehydes and ketones in the presence of catalytic amounts of nickel acetylacetonate.
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DOI:
10.1021/jo00350a065
被引量:
年份:
1985
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