Substrate Stereochemistry of the Enoyl-CoA Hydratase Reaction

1A specimen of stereospecifically 2-tritiated 3-hydroxybutyric acid was prepared by hydroboration of ethyl crotonate. It was assumed that the hydroboration...

P Willadsen，H Eggerer - 《European Journal of Biochemistry》

Differential detection of enantiomeric gaseous analytes using carbon black-chiral polymer composite, chemically sensitive resistors.

Carbon black-chiral polymer composites were used to provide diagnostic differential resistance responses in the presence of enantiomers of chiral gaseous a...

EJ Severin，RD Sanner，BJ Doleman，... - 《Analytical Chemistry》

A novel generation of optically active ethyl 4-chloro-3-hydroxybutyrate as a C4 chiral building unit using microbial dechlorination

A novel procedure for the generation of optically active ethyl 4-chloro-3-hydroxybutyrate using bacterial cells was developed. Ethyl (S)-4-chloro-3-hydroxy...

Toshio，Suzuki，and，... - 《Tetrahedron Asymmetry》

Stereoselective Metabolism of Nicotine and Tobacco-Specific N-Nitrosamines to 4-Hydroxy-4-(3-pyridyl)butanoic Acid in Rats

The carcinogenic tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N'-nitrosonornicotine (NNN) are believed to play a ...

N Trushin，SS Hecht - 《Chemical Research in Toxicology》

Enantioselective physiological effects of the herbicide diclofop on cyanobacterium Microcystis aeruginosa.

Water blooms caused by cyanobacteria are currently major global environmental issues. The outbreaks induced by nutrient elements have attracted much attent...

J Ye，L Wang，Z Zhang，... - 《Environmental Science & Technology》

Enantioselective hydrogenation of β-keto esters catalyzed by chiral binaphthylbisphosphine ruthenium complexes

The catalytic activity and the enantioselectivity manifested by cationic chiral binaphthylbisphosphine ruthenium complexes in asymmetric hydrogenation of ...

VA Pavlov，EV Starodubtseva，MG Vinogradov，... - 《Russian Chemical Bulletin》

Two-Dimensional Chiral HPLC Analysis of Lactate, Hydroxybutyrates and Malate in Human Plasma

For the simultaneous determination of lactate (LA), 2-hydroxybutyrate (2HB), 3-hydroxybutyrate (3HB) and malate (MA) enantiomers, a new separation techniqu...

HM Tsai，CL Hsieh，C Ishii，... - 《Chromatography》

Determination of temporal changes in serum and urinary lactate and 3-hydroxybutyrate enantiomers in mice with nephrotoxic serum nephritis by multi-dimensio...

Nephrotoxic serum (NTS) nephritis occurs in three stages: inflammation, early kidney damage, and severe kidney damage. We quantified the temporal changes i...

PY Lin，SM Chen，CL Hsieh，... - Journal of Pharmaceutical and Biomedical Analysis: An International Journal on All Drug-Related Topics in Pharmaceutical, Biomedical and Clinical Analysis

S-enantiomers of beta-hydroxybutyrate and butanediol and methods for using same

In various embodiments a compound comprising the enantiomerically enriched S-isomer S-BHB-S-1,3-butanediol is provided along with methods of use thereof.

V Eric，JC Newman