First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: discovery of a membrane permeant cADP...

V. L. First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: Discovery of a membrane ...

GK Wagner，S Black，AH Guse，... - 《Cheminform》

First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: discovery of a membrane permeant cADP...

V. L. First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: Discovery of a membrane ...

K Gerd，Wagner，Steven，... - 《Chemical Communications》

First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: discovery of a membrane permeant cADPR agonist

(2003) First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: discovery of a membrane permeant cADPR agonist. Chem. Comm., 1944-5...

GK Wagner，S Black，AH Guse，... - 《Chemical Communications》

First Enzymatic Synthesis of an N1‐Cyclized cADPR (Cyclic‐ADP Ribose) Analogue with a Hypoxanthine Partial Structure: Discovery of a Membrane Permeant cA...

(2003) First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: discovery of a membrane permeant cADPR agonist. Chem. Comm., 1944-5...

GK Wagner，S Black，AH Guse，... - 《Cheminform》

XRCC1 interactions with multiple DNA glycosylases: A model for its recruitment to base excision repair

Repair of chemically modified bases in DNA is accomplished through base excision repair (BER). This pathway is initiated by a specific DNA glycosylase that...

A Campalans，S Marsin，Y Nakabeppu，... - 《Dna Repair》

Defined dimensional changes in enzyme substrates and cofactors. Synthesis of lin-benzoadenosine and enzymic evaluation of derivatives of the benzopurines

A biochemical evaluation of derivatives of 8-aminoimidazo[4,5-g]quinazoline (1), 9-aminoimidazo[4,5-f]quinazoline (2), and 6-aminoimidazo[4,5-h]quinazoline...

NJ Leonard，MA Sprecker，AG Morrice - 《Journal of the American Chemical Society》

Synthesis, characterization, and in vitro evaluation of nitroimidazole-BATO complexes: New technetium compounds designed for imaging hypoxic tissue

Several technetium-99 BATO (boronic acid adduct of technetium dioximes) complexes TcX(dioxime)3BR (X = Cl) that contain a boron cap R which bears a 2- or 4...

KE Linder，YW Chan，JE Cyr，... - 《Bioconjugate Chemistry》

Enzymatic Synthesis of Virazole by Purine Nucleoside Phosphorylase of Enterobacter aerogenes

A potent antiviral agent, Virazole (1--d-ribofuranosyl-1,2,4-triazole-3-carboxamide), was synthesized from inosine and 1,2,4-triazole-3-carboxamide (TCA) by a two step reaction with purified purine nucleoside phosphorylase (PNPase) of En...

U Takashi，M Hirokazu，Y Shigeru，... - 《Journal of the Agricultural Chemical Society of Japan》

Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine-guanine phosphoribosyltransferase.

Hypoxanthine鈥揼uanine phosphoribosyltransferase (HGPRT) (EC 2.4.2.8) is an important enzyme involved in the recycling of purine nucleotides in all cells. ...

PS Monzani，JD Alfonzo，L Simpson，... - 《Biochimica Et Biophysica Acta》

Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine–guanine phosphoribosyltransferase.

Hypoxanthine–guanine phosphoribosyltransferase (HGPRT) (EC 2.4.2.8) is an important enzyme involved in the recycling of purine nucleotides in all cells. P...

Monzani，Paulo，S.，... - 《Bba Proteins & Proteomics》