Current progress in the asymmetric aldol addition reaction.

Control of stereochemistry during aldol addition reactions has attracted considerable interest over the years as the aldol reaction is one of the most fund...

C Palomo，M Oiarbide，Garc?a, Jes?s M. - 《Chemical Society Reviews》

Catalytic asymmetric aldol reaction: reaction of aldehydes with isocyanoacetate catalyzed by a chiral ferrocenylphosphine-gold(I) complex

Control of stereochemistry during aldol addition reactions has attracted considerable interest over the years as the aldol reaction is one of the most fund...

Yoshihiko.，Ito，Masaya.，... - 《Journal of the American Chemical Society》

Enantio- and diastereoselective aldol reactions of achiral ethyl and methyl ketones with aldehydes: the use of enol diisopinocampheylborinates

Enol diisopinocampheylborinates, derived from achiral ethyl and methyl ketones by enolisation in the presence of tertiary amine bases ( iPr 2NEt or Et 3N),...

I Paterson，JM Goodman，MA Lister，... - 《Tetrahedron》

Synthetic control leading to chiral compounds

A highly diastereoselective cross aldol reaction is developed using divalent tin enolates formed from stannous trifluoromethanesulfonate and carbonyl compounds. The reaction is extended to a highly enantioselective cross aldol reaction e...

T Mukaiyama，N Iwasawa，RW Stevens，... - 《Tetrahedron》

Direct asymmetric aldol reactions between aldehydes and ketones catalyzed by L-tryptophan in the presence of water

Primary amino acids and their derivatives were investigated as catalysts for the direct asymmetric aldol reactions between ketones and aldehydes in the pre...

Z Jiang，Y Hui，H Xiao，... - 《Organic & Biomolecular Chemistry》

Enantio‐ and Diastereoselective Aldol‐Reaction of 2,6‐Dimethylphenyl Propionate Using Titanium‐Carbohydrate Complexes

Chloro(cyclopentadienyl)bis(1,2:5,6-di- O -isopropylidene-α- D -glucofuranos-3- O -yl)titanium ( 1 ) is used for the transmetallation of Li-enolates obtained from propionyl derivatives. While such Ti-enolates of ketones and hydrazones a...

RO Duthaler，P Herold，S Wyler‐Helfer，... - 《Helvetica Chimica Acta》

ACYCLIC STEREOSELECTION .45. SYNTHESIS OF ETA-1 OXYGEN-BOUND RHODIUM ENOLATES - APPLICATIONS TO CATALYTIC ALDOL CHEMISTRY

Chloro(cyclopentadienyl)bis(1,2:5,6-di- O -isopropylidene-α- D -glucofuranos-3- O -yl)titanium ( 1 ) is used for the transmetallation of Li-enolates obtained from propionyl derivatives. While such Ti-enolates of ketones and hydrazones a...

GA Slough，RG Bergman，CH Heathcock

Stannous triflate mediated aldol reaction of 3-acylthiazolidine-2-thione: A convenient method for the stereoslective syntheses of .BETA.-hydroxy aldehyde a...

No abstract is available for this article.

T Mukaiyama，N Iwasawa - 《Cheminform》

A General Method for the Synthesis of Both Enantiomers of Optically Pure β-Hydroxy Esters from (S)-(p-Chlorophenylsulfinyl)acetone Easily Obtainable by Kinetic Resolution with Bakers’ Yeast

Both enantiomers of various optically pure (R)- and (S)-β-hydroxy esters were generally synthesized from (S)-(p-chlorophenylsulfinyl)acetone obtained by kinetic resolution with bakers’ yeast, followed by γ-alkylation, diastereoselecti...

T Fujisawa，A Fujimura，T Sato - 《Bulletin of the Chemical Society of Japan》

Highly enantioselective aldol reaction mediated by mixed aggregates derived from a lithium ester enolate and tetradentate chiral lithium amides

Both enantiomers of various optically pure (R)- and (S)-β-hydroxy esters were generally synthesized from (S)-(p-chlorophenylsulfinyl)acetone obtained by kinetic resolution with bakers’ yeast, followed by γ-alkylation, diastereoselecti...

M Uragami，K Tomioka，K Koga