Cost of Relapse in Schizophrenia

To estimate the national annual cost of rehospitalization for multiple-episode schizophrenia outpatients, and to determine the relative cost burden from lo...

PJ Weiden，O Mark - 《Schizophr Bull》

Clozapine-induced agranulocytosis. Incidence and risk factors in the United States.

Clozapine is an atypical antipsychotic agent that is more effective than standard neuroleptic drugs in the treatment of patients with refractory schizophre...

JMJ Alvir，JA Lieberman，AZ Safferman，... - 《New England Journal of Medicine》

Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborati...

OBJECTIVE: This international, multicenter double-blind trial was designed to compare the therapeutic profile of an atypical antipsychotic, olanzapine, wit...

GD Tollefson，CM Beasley，PV Tran，... - 《Am J Psychiatry》

Olanzapine versus placebo and haloperidol: acute phase results of the North American double-blind olanzapine trial.

Olanzapine is a potential new "atypical" antipsychotic agent. The double-blind acute phase of this study compared three dosage ranges of olanzapine (5卤2.5...

CMB Jr，G Tollefson，P Tran，... - 《Neuropsychopharmacology》

A comparison of clozapine and haloperidol in hospitalized patients with refractory schizophrenia. Department of Veterans Affairs Cooperative Study Group on...

BACKGROUND: Clozapine, a relatively expensive antipsychotic drug, is widely used to treat patients with refractory schizophrenia. It has a low incidence of...

R Rosenheck，J Cramer，W Xu，... - 《N Engl J Med》

The long QT syndromes: A critical review, new clinical observations and a unifying hypothesis

BACKGROUND: Clozapine, a relatively expensive antipsychotic drug, is widely used to treat patients with refractory schizophrenia. It has a low incidence of...

Warren，M.，Jackman，... - 《Progress in Cardiovascular Diseases》

Olanzapine versus Placebo and Haloperidol

Neuropsychopharmacology, the official publication of the American College of Neuropsychopharmacology, publishing the highest quality original research and ...

CM Beasley，G Tollefson，P Tran，... - 《Neuropsychopharmacology》

A Canadian Multicenter Placebo-Controlled Study of Fixed Doses of Risperidone and Haloperidol in the Treatment of Chronic Schizophrenic Patients

In a double-blind study, 135 inpatients with a diagnosis of chronic schizophrenia were randomly assigned to 8 weeks of treatment with one of six parallel t...

G Chouinard，B Jones，G Remington，... - 《Journal of Clinical Psychopharmacology》

Effects of a limit on Medicaid drug-reimbursement benefits on the use of psychotropic agents and acute mental health services by patients with schizophrenia.

BACKGROUND: We examined the effects of a three-prescription monthly payment limit (cap) on the use of psychotropic drugs and acute mental health care by no...

Soumerai, Stephen B.，McLaughlin, Thomas J.，Ross-Degnan, Dennis，... - 《N Engl J Med》

Cost of relapse in schizophrenia.

To estimate the national annual cost of rehospitalization for multiple-episode schizophrenia outpatients, and to determine the relative cost burden from lo...

P J，Weiden，Olfson - 《Schizophrenia Bulletin》