Secreted and transmembrane polypeptides and nucleic acids encoding the same

The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and hos...

Baker, Kevin P，Chen, Jian，Desnoyers, Luc，... - J Trauma

Modulation of nitric oxide synthase by PKC

Featured are methods of modulating endothelial NOS (eNOS) expression, e.g., insulin-stimulated eNOS expression, by modulating PKCβ. The methods are useful in the treatment of insulin-related disorders, e.g., hypertension.

King, George L - US

DNA METHYLATION ANALYSIS BY DIGITAL BISULFITE GENOMIC SEQUENCING AND DIGITAL METHYLIGHT

Provided are novel sensitive methylation assays referred to herein as Digital MethyLight, comprising stochastically distributing and compartmentalizing bis...

PW Laird，BN Trinh，M Campan，... - 《Nucleic Acids Research》

Methods for treating viral infection using IL-28 and IL-29 cysteine mutants

IL-28A, IL-28B, IL-29, and certain mutants thereof have been shown to have antiviral activity on a spectrum of viral species. Of particular interest is the antiviral activity demonstrated on viruses that infect liver, such as hepatitis B...

KM Klucher，WR Kindsvogel，PV Sivakumar，... - US

Metabolic phenotyping via administration of probe for HMG CoA reductase inhibitor (hydroxy-3-methylglutaryl/3-coenzyme A); comprises microgravimetric sensors

The invention relates to the individualization of therapy on the basis of a phenotypic profile of an individual. More specifically, the present invention r...

B Leyland-Jones - US

ANTIMICROBIAL MATERIAL

The present invention relates to nanoparticles containing a non-persistent support material and metallic silver particles on the surface of said support ma...

S Bokorny，WJ Stark，SF Loher - 《造纸与生物质材料:英文版》

Modified peptides as therapeutic agents

The present invention concerns fusion of Fc domains with biologically active peptides and a process for preparing pharmaceutical agents using biologically active peptides. In this invention, pharmacologically active compounds are prepare...

U Feige，Liu, Chun-fa，Cheetham, Janet C，... - US

Ionic liquid high temperature gas sensors

An ionic liquid piezoelectric gas sensor was demonstrated for detection of polar and nonpolar organic vapors at high temperature with fast linear and rever...

L Yu，D Garcia，R Ren，... - 《Chemical Communications》

IDENTIFICATION OF A NOVEL BITTER TASTE RECEPTOR, T2R76

not available

JE Adler，H Tang，A Pronin，... - WO

METHOD OF MEASURING LOW DENSITY LIPOPROTEIN (LDL) CHOLESTEROL AND TEST PIECE FOR MEASURING LDL CHOLESTEROL

An LDL cholesterol measurement method that can be used with a test piece is provided. The LDL cholesterol measurement method for measuring LDL cholesterol in a sample has (A) a step of providing a total-cholesterol measurement portion an...

YAMAGUCHI TAKEHIRO，MIYAKE YUKA - US